ENHANCING CHEMOIMMUNOTHERAPY FOR COLORECTAL CANCER WITH PACLITAXEL AND ALANTOLACTONE VIA CD44-TARGETED NANOPARTICLES: A STAT3 SIGNALING PATHWAY MODULATION APPROACH

Chemoimmunotherapy has the potential to enhance chemotherapy and modulate the immunosuppressive tumor microenvironment by activating immunogenic cell death (ICD), making it a promising strategy for clinical application.Alantolactone (A) was found to augment the anticancer efficacy of paclitaxel (P) at a molar ratio of 1:0.5 (P:A) through induction

RGB Led Strip A healthy lawn is an important component of an urban landscape.Not only do lawns increase the value of a property, but they also reduce soil erosion, filter stormwater runoff, cool the air, and reduce glare and noise.A healthy lawn effectively filters and traps sediment and pollutants that could otherwise contaminate surface waters an

Investigating the dynamic response patterns and failure modes of concrete gravity dams subjected to strong earthquakes is a pivotal area of research for addressing seismic safety concerns associated with gravity dam structures.Dynamic shaking table testing has proven to EXTRA-HOLD SHAPING SPRAY be a robust methodology for exploring the dynamic char

This research has studied the possibility of optimizing some of the properties of the precast concrete flags by using by-products of steel fragments from the CNC machines and local slag, the combined influence of these materials338with the water reducing agent.The local slag is produced by the blast furnace from the scrap as a raw material, which i

The genetic diversity and growth dynamics of fifty-three half-sib families of eleven provenance sources and one bulk seed mixed population of fast growing forest tree species i.e.Melia azedarach were studied at two stand ages viz., fourth year (mid-rotation) and eighth year (end-rotation) to determine the selection stage in northern India.Significa